Increased Axon Number in the Anterior Commissure of Mice Lacking a Corpus Callosum
نویسندگان
چکیده
منابع مشابه
Increased axon number in the anterior commissure of mice lacking a corpus callosum.
Relatively few behavioral deficits are apparent in subjects with hereditary absence of the corpus callosum (CC). The anterior commissure (AC) has been suggested to provide an extracallosal route for the transfer of interhemispheric information in subjects with this congenital defect. Anterior commissure size, axon number, axon diameter, and neuronal distribution were compared between normal mic...
متن کاملRetarded formation of the hippocampal commissure in embryos from mouse strains lacking a corpus callosum.
A precise description of the timing and route traveled by axons traversing the telencephalic midline through the ventral hippocampal commissure (HC) is essential for understanding the role it plays in the formation of the corpus callosum (CC). A normal baseline of HC development was described in B6D2F2 hybrid mice and then compared with two inbred strains of mice displaying callosal agenesis, B...
متن کاملAnterior Commissure - Posterior Commissure Revisited
OBJECTIVE The anterior commissure (AC) and posterior commissure (PC) are the two distinct anatomic structures in the brain which are difficult to observe in detail with conventional MRI, such as a 1.5T MRI system. However, recent advances in ultra-high resolution MRI have enabled us to examine the AC and PC directly. The objective of the present study is to standardize the shape and size of the...
متن کاملAxon position within the corpus callosum determines contralateral cortical projection.
How developing axons in the corpus callosum (CC) achieve their homotopic projection to the contralateral cortex remains unclear. We found that axonal position within the CC plays a critical role in this projection. Labeling of nearby callosal axons in mice showed that callosal axons were segregated in an orderly fashion, with those from more medial cerebral cortex located more dorsally and subs...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 1997
ISSN: 0014-4886
DOI: 10.1006/exnr.1997.6564